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Palatal perforation due to disseminated histoplasmosis as the first presentation of HIV-AIDS

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Case Report

Author Details : Archana Lakshmanan*, Radhika M , Jithesh Balan, Rajesh K.R

Volume : 10, Issue : 2, Year : 2023

Article Page : 46-49

https://doi.org/10.18231/j.sajcrr.2023.010

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Abstract

Histoplasmosis is a systemic fungal infection caused by H. capsulatum usually in immunocompromised individuals such as those with HIV-AIDS. Though oral manifestations are rare, they could be the only and initial manifestation of HIV-AIDS. We report the case of a 23-year-old female who presented with oral ulcer and palatal perforation and detected to be suffering from disseminated histoplasmosis. She also turned out to be HIV positive. Her CD4+ count was undetectable. She responded well to intravenous liposomal Amphotericin B, oral itraconazole and antiretroviral therapy. To the best of our knowledge, histoplasmosis presenting as palatal perforation as the first manifestation of HIV-AIDS has not been reported from South India previously. A high index of suspicion is needed in such cases of exaggerated oral lesions even in states like Kerala to avoid delay in diagnosis and therapy.

Keywords: Histoplasma capsulatum, Oral histoplasmosis, Palatal perforation, Acquired immunodeficiency syndrome, HIV

How to cite : Lakshmanan A, Radhika M, Balan J, K.r R, Palatal perforation due to disseminated histoplasmosis as the first presentation of HIV-AIDS. South Asian J Case Rep Rev 2023;10(2):46-49

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