Southeast Asian Journal of Case Report and Review

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Southeast Asian Journal of Case Report and Review is a Peer-reviewed, International medical journal Published by the Association of Health Professionals. It will publish 04 issues per year will publish a research paper prepared by Health Professional. Journal will Give Preference to Case Report and Review Article   Aim and Scope The aim and commitment of the journal is to publish a research-oriented manuscript on significant issues in all the subjects and areas of Medical Science including Genome mutation and Pathogenicity in microbes. Journal more...

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Get Permission Nikitha, Nishanth, and Ruchitha: Liver abscess: A case study


Introduction

Liver is an important and vital organ of the body.1 Liver abscess is a suppurative lesion in the liver formed as a result of invasion and multiplication of microorganisms which gain access by entering directly from an injury through the blood vessels or by the biliary ductal system.2 septicemia, direct infection latrogenic, cryptogenic, etc.3

Pyrogenic liver abscess (PLA)

PLA is a pocket of pus that forms in the liver due to bacterial infection (pyrogenic) which have become uncommon due to improved diagnostic facilities and the early use of antibiotics.

This incidence is higher in older age and in immunosuppressed patients such as AIDS, transplant recipients and those on intensive chemotherapy.3

Table 1

Department of pathology (Complete Blood Picture)

Test Description

Results

Units

Ref. Range

Methodology

WBC

11.8

103/ul

4.0-11.0 103/ul

Flow cytometry

RBC

3.5

106/ul

4.5-5.5 106/ul

Flow cytometry

Hemoglobin

10.9

g/dl

13.0-17.0 g/dl

SLS method

Neutrophils

83

%

40-80%

Flow cytometry/ manual

Lymphocytes

10

%

20-40%

Flow cytometry/ manual

Monocytes

06

%

2-10%

Flow cytometry/ manual

Eosinophils

01

%

1-6%

Flow cytometry/ manual

Basophils

00

%

<1-2%

Flow cytometry/ manual

Platelet Count

4.46

Lakhs/Cum m

1.50-4.50 lakhs/cumm

Flow cytometry/ manual

ESR

120

mm

0-15mm 1st hour

Westerng

Table 2

Department of biochemistry (Serum electrolytes)

Test Descripti On

Results

Units

Ref. Range

Methodo Logy

Sodium

138

mmol/L

136-145 mmol/L

ISE direct

Potassium

4.1

mmol/L

3.5-5.1 mmol/L

ISE direct

Chlorides

102

mmol/L

98-107 mmol/L

ISE direct

Table 3

Department of biochemistry (Liver profile, Random blood sugar, blood urea, serum creatinine)

Test descripti on

Results

Units

Ref. Range

Methodo logy

Serum Total Protein

6.3

g/dl

6-8 g/dl

Biuret

Serum Albumin

3.4

g/dl

3.5-5.2 g/dl

BCG

Serum Globulin

2.9

g/dl

1.8-3.6 g/dl

Calculative

A/G ratio

1.1

1.2-1.7

Calculative

Serum Total Bilirubin

0.4

mg/dl

0.2-2.0 mg/dl

Diazo Colorimetric

Serum Direct Bilirubin

0.2

mg/dl

0-0.2 mg/dl

Diazo Colorimetric

Serum Indirect Bilirubin

0.2

mg/dl

0.1-1.0 mg/dl

Calculative

SGPT (ALT)

36

U/L

5-45 U/L

IFCC kinetic with pyridoxal phosphate

SGOT (AST)

35

U/L

5-35 U/L

IFCC kinetic with pyridoxal phosphate

ALP

245

U/L

53-128 U/L

Kinetic photometric method IFCC

Gamma GT

347

U/L

1-55 U/L

IFCC

Random Blood Sugar

94

mg/dl

70-160 mg/dl

GOD-PAP

Blood Urea

14

mg/dl

10-50 mg/dl

Urease

Serum Creatinine

0.8

mg/dl

0.9-1.3 mg/dl

JAFFE’S (kinetic)

Table 4

Department of pathology

Test descripti on

Results

Units

Ref. Range

Methodo logy

Prothrombin time

25.2

seconds

13.6 seconds

APTT

37.9

seconds

30 seconds

Table 5

Department of microbiology (HBsAG, HIV, HCV)

HBS AG (Spot Test):

Test description

Results

Methodology

Hepatitis B Surface antigen (HBsAG)

Non- reactive

Rapid Immunochromatographic (Card method)

HIV (TRIDOT):

Test Description

Results

Methodology

HIV 1 and 2 antibodies

Non- reactive

Flow through technology (Card method)

HCV:

Test Description

Results

Methodology

Hepatitis C virus

Non- reactive

Flow through technology (Card method)

Table 6

Department of microbiology

Test descripti on

Results

Units

Ref. Range

Methodo logy

MP PV/PF Malarial parasite (P.F & PAN)

Positive for PAN

Immuno Chromatography

Morphological feature

Depending upon the cause,

• For pyrogenic liver abscess, they occur as single or multiple yellow abscesses, 1cm or more in diameter in an enlarged liver.3

Amoebic Liver Abscess (ALA)

ALA are less common than pyrogen liver abscess and have similar features. They are caused by the spread of Entamoeba Histolytica from intestinal lesions.

The trophozoite form of amoeba in the colon invade the colonic mucosa forming flask- shaped ulcers from where they are carried to the liver in portal venous system.

Amoeba multiply and block small intrahepatic portal radicles resulting in infarction necrosis of the adjacent liver parenchyma.

Morphological feature

  1. ALA may vary greatly in size but is generally of the size of an organ.

  2. The Centre of the abscess contains large necrotic area having reddish-brown, thick pus resembling anchovy or chocolate sauce

  3. The abscess wall consists of irregular shreds of necrotic liver tissue.

History

This case involves P. Kankaiah aged 52 years in Chalmeda Anand rao Institute of Medical Sciences (CAIMS). It had occurred in 2020. He consulted the doctor with symptoms of low-grade fever for 20 days, continuous associated with chills and rigors, pain in abdomen in right hypochondriac and right lumbar, indigestion, constipation.

Past medical history

The person doesn't own cold/cough, burning micturition, diabetes mellitus, hypertension, coronary artery disease, cerebrovascular accident.2

The person possesses symptoms like indigestion, constipation, fever.1

Social history

Previously the patient is chronic alcoholic for 20 years and stopped before 1year and chronic smoker.

Discussion

Patient was ordered to test for the following:

  1. Complete blood picture with erythrocyte sedimentation rate

  2. Random blood sugar

  3. Human immunodeficiency virus, hepatitis B surface antigen, hepatitis C virus

  4. Blood Urea

  5. Serum Creatinine

  6. Serum Electrolytes

  7. Liver function tests

  8. Malaria- (Plasmodium falciparum and plasmodium vivax)

  9. Prothrombin time and activated partial thromboplastin time (APTT)

Results

These are the results for the patient performed to find out disease from which he is suffering.

Source of Funding

None.

Conflict of Interest

None.

References

1 

A Dutta S Kishangunj Management of liver abscessMed Update20122246975

2 

P N Sreeramulu V S D Swamy N Suresh S Suma Liver abscess: presentation and an assessment of the outcome with various treatment modalitiesInt Surg J201967224

3 

Harshmohan Textbook of pathology6th 20106145



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Article type

Case Report


Article page

12-14


Authors Details

G Nikitha, S. Nishanth, D. Ruchitha


Article History

Received : 08-04-2022

Accepted : 14-04-2022


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